This is an aptamer development services to screening aptamers binds to the BTG1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BTG1 |
| Alternative Names | BTG Anti-Proliferation Factor 1; B-Cell Translocation Gene 1, Anti-Proliferative; B-Cell Translocation Gene 1 Protein; Protein BTG1; APRO2 |
| Gene ID | 694 |
| UniProt ID | P62324 |
| Target Overview | This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |