This product is an aptamer which binds to the CTSG with a high affinity.
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| Target Category | Protein |
| Target | CTSG |
| Alternative Names | Cathepsin G |
| Gene ID | 1511 |
| UniProt ID | P08311 |
| Target Overview | The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is an Amino Modifiedtimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. |
| Chemical Modification | DNA |
| Length | 40-60 nt |
| Affinity (Kd) | N/A |
| Binding Conditions/Buffer | 30 mM Tris HCl pH7.5, 150 mM NaCl, 5 mM KCl and 5 mM MgCl2. |
| GC Content | 0.5 |
| Molecular Weight | 18688 |
| nmoles/OD260 | 1.54 |