Anti-CD133 Aptamer(Cat#: CTApt-M-684)

This product is an aptamer which binds to the PROM1 with an affinity of <200 nM.

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Summary

Specifications
Target Category Protein
Target PROM1
Alternative Names Prominin 1 ; CORD12 ; PROML1; AC133; CD133 ; RP41; Prominin-Like Protein 1; Antigen AC133 ; Prominin-1; MCDR2; STGD4; Stargardt Disease 4 (Autosomal Dominant) ; Hematopoietic Stem Cell Antigen ; Macular Dystrophy, Retinal 2 ; Prominin (Mouse)-Like 1 ; CD133 Antigen ; HProminin ; MSTP061
Gene ID 8842
UniProt ID P40763
Target Overview This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Chemical Modification RNA
Length 20-40 nt
Affinity (Kd) <200 nM
Binding Conditions/Buffer DPBS with 2.5 mM MgCl2, 0.1 mg/mL tRNA and 0.1 mg/mL salmon sperm DNA.
GC Content 0.6
Molecular Weight 4470.9
nmoles/OD260 6.522
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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