Anti-CD163 Aptamer SELEX Service(Cat#: CTApt-709)

This is an aptamer development services to screening aptamers binds to the CD163 with an affinity of 1nM~1μM.

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Certificate of Analysis Lookup

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Lot Number

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Summary

Specifications
Target Category Protein
Target CD163
Alternative Names M130; MM130; SCARI1
Gene ID 9332
UniProt ID Q86VB7
Target Overview The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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