Anti-CD3 Aptamer(Cat#: CTMM-1024-MM2)
This product is a customized aptamer which binds to human and mouse CD3 with an affinity of 50-100 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
CD3 |
| Alternative Names |
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3 |
| Gene ID |
916 |
| UniProt ID |
P07766 |
| Target Overview |
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex. |
| Type |
DNA |
| Species Reactivity |
Mouse; Human |
| Length |
50-100 nt |
| Affinity (Kd) |
<100 nM |
| Binding Conditions/Buffer |
150 Mm NaCl, 2 mM CaCl2, 20 mM HEPES, and 0.01% BSA, pH 7.4 |
| GC Content |
52.00% |
| Molecular Weight |
79.4 |
| Extinction Coefficient |
30516.9 |
| nmoles/OD260 |
0.906 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
