Anti-CD44 Aptamer-CTApt-M-057 (CTApt-M-057)

Specifications

Target Category	Protein
Target	CD44
Alternative Names	CD44 Molecule (Indian Blood Group) ; HCELL ; CSPG8 ; MC56 ; Pgp1; MDU2; MDU3; MIC4 ; IN ; Hematopoietic Cell E- And L-Selectin Ligand ; GP90 Lymphocyte Homing/Adhesion Receptor ; Chondroitin Sulfate Proteoglycan 8 ; Extracellular Matrix Receptor III ; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein 1 ; Hyaluronate Receptor ; Hermes Antigen; CD44 Antigen ; ECMR-III; HUTCH-I ; Epican; CD44R ; LHR ; CD44 Antigen (Homing Function And Indian Blood Group System) ; Homing Function And Indian Blood Group System ; Cell Surface Glycoprotein CD44 ; Indian Blood Group Antigen ; Phagocytic Glycoprotein I ; Soluble CD44 ; CDW44 ; CDw44 ; PGP-1 ; PGP-I
Gene ID	960
UniProt ID	P40763
Target Overview	The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Chemical Modification	2'F-RNA
Length	80-100 nt
Affinity (Kd)	<100 nM
Binding Conditions/Buffer	4.2mM Na2HPO4, 2mM K2HPO4, 140mM NaCl, 10mM KCl, 2.5mM MgCl2.
GC Content	0.48
Molecular Weight	27747.6
nmoles/OD260	0.959

Anti-CD44 Aptamer-CTApt-M-057(Cat#: CTApt-M-057)

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