Anti-CLDN3 Aptamer SELEX Service(Cat#: CTApt-719)

This is an aptamer development services to screening aptamers binds to the CLDN3 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target CLDN3
Alternative Names RVP1; HRVP1; C7orf1; CPE-R2; CPETR2
Gene ID 1365
UniProt ID O15551
Target Overview Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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