Anti-COPA Aptamer SELEX Service(Cat#: CTApt-2323)
This is an aptamer development services to screening aptamers binds to the COPA with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
COPA |
| Alternative Names |
COPI Coat Complex Subunit Alpha; HEP-COP; Coatomer Subunit Alpha; Alpha-COP; Proxenin; Xenin; Coatomer Protein Complex, Subunit Alpha; Coatomer Protein Complex Subunit Alpha; Alpha Coat Protein; Alpha-Coat Protein; HEPCOP; AILJK; COPA |
| Gene ID |
1314 |
| UniProt ID |
P53621 |
| Target Overview |
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
