Anti-Creatinine Aptamer(Cat#: CTApt-865)

Name: Anti-Creatinine Aptamer
SKU: CTApt-865

This product is an aptamer which binds to the Creatinine with an affinity of <50 µM.

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Specifications

Target Category	Small Organic
Target	Creatinine
Target Overview	Creatinine is a waste product that comes from the normal wear and tear on muscles of the body. Everyone has creatinine in their bloodstream.
Chemical Modification	DNA
Length	40-60 nt
Affinity (Kd)	<50 µM
Binding Conditions/Buffer	20 mM HEPES, 1 M NaCl, 10 mM MgCl2, 5 mM KCl, pH 7.5.
GC Content	0.42
Molecular Weight	16514.8
nmoles/OD260	1.65

Background

Creatinine, a metabolic byproduct of muscle metabolism, serves as a vital indicator of renal function due to its consistent production and clearance primarily through glomerular filtration. However, conventional methods for creatinine detection often lack specificity and sensitivity, limiting their efficacy in certain experimental settings. In response, anti-creatinine aptamers offer a promising alternative. These single-stranded DNA or RNA molecules bind to creatinine specifically and with high affinity. This aptamer is primarily used as a research tool for studying renal dysfunctions or for developing creatinine detection assays.

Customer Review

Successful ELONA of creatinine with aptamers

Excellent

I am interested in ELONA for the determination of creatinine. Then I purchased the anti-creatinine aptamer and successfully applied it to the assay.

The ideal target molecule for in vivo imaging

Excellent

The small size of the aptamer led to its modification into an aptamer-based probe. This helped me to observe the distribution and levels of creatinine in vivo during the progression of kidney disease. And the end result was good.

Measure creatinine levels with anti-creatinine aptamer

Excellent

My experience with this aptamer is that it is selective and stable, and easier to control and cheaper than other reagents.

The purity and effectiveness of this product is truly commendable

Excellent

This anti-creatinine aptamer is a dream come true for a Bio-lab like ours. It worked as expected for our research. We also appreciate the technical guidance provided by the seller which made our work a lot easier.

The product did perform well and delivered satisfactory results

Excellent

As a professor in biochemical research, I can vouch for the anti-creatinine aptamer's high quality. It's become an invaluable tool in our lab, and its consistent performance has made our testing far more accurate and efficient.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.

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