This is an aptamer development services to screening aptamers binds to the CTNNA1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | CTNNA1 |
| Alternative Names | Catenin Alpha 1; Renal Carcinoma Antigen NY-REN-13; Alpha-E-Catenin; Catenin Alpha-1; CAP102; Catenin (Cadherin-Associated Protein), Alpha 1 (102kD) ; Catenin (Cadherin-Associated Protein), Alpha 1, 102kDa; Epididymis Secretory Sperm Binding Protein; Cadherin-Associated Protein; Alpha E-Catenin; CTNNA1; MDPT2 |
| Gene ID | 1495 |
| UniProt ID | P35221 |
| Target Overview | This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |