Anti-CX3CL1 Aptamer(Cat#: CTApt-M-029)
This product is an aptamer which binds to the CX3CL1 with an affinity of <20 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
CX3CL1 |
| Alternative Names |
C-X3-C Motif Chemokine Ligand 1 ; Fractalkine; Neurotactin ; C3Xkine; ABCD-3; CXC3C; SCYD1; CXC3 ; NTN ; Small Inducible Cytokine Subfamily D (Cys-X3-Cys), Member 1 (Fractalkine, Neurotactin) ; Chemokine (C-X3-C Motif) Ligand 1; CX3C Membrane-Anchored Chemokine ; Small-Inducible Cytokine D1 ; C-X3-C Motif Chemokine 1 ; NTT; Small Inducible Cytokine Subfamily D (Cys-X3-Cys), Member-1 ; FKN |
| Gene ID |
6376 |
| UniProt ID |
P40763 |
| Target Overview |
This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. |
| Chemical Modification |
DNA |
| Length |
20-40 nt |
| Affinity (Kd) |
<20 nM |
| GC Content |
0.8 |
| Molecular Weight |
12684.2 |
| nmoles/OD260 |
2.297 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
