This product is an aptamer which binds to the Cyanocobalamin with an affinity of <100 nM.
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| Target Category | Small Organic |
| Target | Cyanocobalamin |
| Alternative Names | vitamin B12 |
| Target Overview | Cyanocobalamin is a man-made form of vitamin B12 used to prevent and treat low blood levels of this vitamin. |
| Chemical Modification | RNA |
| Length | 20-40 nt |
| Affinity (Kd) | <100 nM |
| Binding Conditions/Buffer | 1 M LiC1, 5 mM MgCl2, and 25 mM HEPES (pH 7.4) or 1 M NaCl, 5 mM MgC12, and 25 mM HEPES (pH 7.4). |
| GC Content | 0.6 |
| Molecular Weight | 11263.9 g/mole |
| Extinction Coefficient | 341600 L/(mole·cm) |
| nmoles/OD260 | 2.93 |