Anti-Daunomycin Aptamer(Cat#: CTMM-0422-MM9)

This product is an aptamer which binds to the Daunomycin with an affinity of <300 nM.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Small Organic
Target Daunomycin
Alternative Names Daunorubicin
Target Overview Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. Specifically it is used for acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), and Kaposi's sarcoma.
Chemical Modification DNA
Length 20-40 nt
Affinity (Kd) <300 nM
Binding Conditions/Buffer 20 mM Tris-HCl (pH 7.4), 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, 1 mM CaCl22, and 0.05% v/v Tween-20.
GC Content 0.5676
Molecular Weight 11581.57 g/mole
Extinction Coefficient 366800 L/(mole·cm)
nmoles/OD260 2.73
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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