This product is an aptamer which binds to the Daunomycin with an affinity of <300 nM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Small Organic |
| Target | Daunomycin |
| Alternative Names | Daunorubicin |
| Target Overview | Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. Specifically it is used for acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), and Kaposi's sarcoma. |
| Chemical Modification | DNA |
| Length | 20-40 nt |
| Affinity (Kd) | <300 nM |
| Binding Conditions/Buffer | 20 mM Tris-HCl (pH 7.4), 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, 1 mM CaCl22, and 0.05% v/v Tween-20. |
| GC Content | 0.5676 |
| Molecular Weight | 11581.57 g/mole |
| Extinction Coefficient | 366800 L/(mole·cm) |
| nmoles/OD260 | 2.73 |