This product is an aptamer which binds to the Daunomycin with an affinity of <300 nM.
Target Category | Small Organic |
Target | Daunomycin |
Alternative Names | Daunorubicin |
Target Overview | Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. Specifically it is used for acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myelogenous leukemia (CML), and Kaposi's sarcoma. |
Chemical Modification | DNA |
Length | 20-40 nt |
Affinity (Kd) | <300 nM |
Binding Conditions/Buffer | 20 mM Tris-HCl (pH 7.4), 140 mM NaCl, 5 mM KCl, 1 mM MgCl2, 1 mM CaCl22, and 0.05% v/v Tween-20. |
GC Content | 0.5676 |
Molecular Weight | 11581.57 g/mole |
Extinction Coefficient | 366800 L/(mole·cm) |
nmoles/OD260 | 2.73 |