This is an aptamer development services to screening aptamers binds to the ENPEP with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ENPEP |
| Alternative Names | Glutamyl Aminopeptidase; Differentiation Antigen Gp160; Aminopeptidase A; EC 3.4.11.7; CD249; Gp160; AP-A; EAP; Glutamyl Aminopeptidase (Aminopeptidase A) ; CD249 Antigen; EC 3.4.11; ENPEP; APA |
| Gene ID | 2028 |
| UniProt ID | Q07075 |
| Target Overview | The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |