Anti-EPHB4 Aptamer SELEX Service(Cat#: CTApt-742)

This is an aptamer development services to screening aptamers binds to the EPHB4 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target EPHB4
Alternative Names HTK; MYK1; HFASD; CMAVM2; LMPHM7; TYRO11
Gene ID 2505
UniProt ID P54760
Target Overview Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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