Anti-ErbB2 Aptamer(Cat#: CTApt-038)

This product is an aptamer which binds to the ErbB2 in Breast Cancer Cells with an affinity of <20 nM.

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5’ Modification
 
3’ Modification
 
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Summary Customer Reviews

Specifications
Target Category Protein
Target ErbB2 in Breast Cancer Cells
Chemical Modification 2'-F-RNA
Length 20-40 nt
Affinity (Kd) <20 nM
Binding Conditions/Buffer Binding buffer: 20 mM HEPES (pH 7.0), 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, and 40 U RNase Inhibitor
GC Content 0.7353
Molecular Weight 11239.85 g/mole
Extinction Coefficient 341100 L/(mole·cm)
nmoles/OD260 2.93

Customer Review

For detecting ErbB2 in samples
Excellent
The assay was quick and easy to perform, and we obtained reliable results.
Easy to use
Excellent
It worked very well in our experiments, and we were able to detect ErbB2 with high sensitivity.
A powerful tool for studying ErbB2
Excellent
We have used the ErbB2 (SE15-8) aptamer for detecting ErbB2 in cancer cell lines and found it to be highly effective. The assay was easy to optimize, and we obtained consistent results every time.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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