This product is an aptamer which binds to the ErbB2 in Breast Cancer Cells with an affinity of <20 nM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | ErbB2 in Breast Cancer Cells |
| Chemical Modification | 2'-F-RNA |
| Length | 20-40 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | Binding buffer: 20 mM HEPES (pH 7.0), 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, and 40 U RNase Inhibitor |
| GC Content | 0.7353 |
| Molecular Weight | 11239.85 g/mole |
| Extinction Coefficient | 341100 L/(mole·cm) |
| nmoles/OD260 | 2.93 |
For detecting ErbB2 in samplesExcellentThe assay was quick and easy to perform, and we obtained reliable results.
Easy to useExcellentIt worked very well in our experiments, and we were able to detect ErbB2 with high sensitivity.
A powerful tool for studying ErbB2ExcellentWe have used the ErbB2 (SE15-8) aptamer for detecting ErbB2 in cancer cell lines and found it to be highly effective. The assay was easy to optimize, and we obtained consistent results every time.