This product is an aptamer which binds to the Extracellular Regulated Kinase 1 and 2 (ERK 1 and ERK2) with an affinity of <20 nM.
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| Target Category | Protein |
| Target | Extracellular Regulated Kinase 1 and 2 (ERK 1 and ERK2) |
| Chemical Modification | RNA |
| Length | 100-150 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | Buffer: 10 mM HEPES, pH 7.5; 10 mM MgCl2 |
| GC Content | 0.4587 |
| Molecular Weight | 35091.26 g/mole |
| Extinction Coefficient | 1100300 L/(mole·cm) |
| nmoles/OD260 | 0.91 |
Highly recommendedExcellentUsing the anti-ERK-1/ERK2 aptamer from Creative Biolabs has been a game-changer for our research. The aptamer showed excellent binding affinity and specificity, allowing us to selectively target ERK signaling pathways.
Great productExcellentIt effectively inhibited ERK activity in our cell culture experiments, leading to significant changes in downstream signaling. The quality of the aptamer was excellent, and the results were highly reliable.
Timely delivery and great supportExcellentIt was instrumental in our study, allowing us to specifically target ERK proteins and investigate their role in disease.