This is an aptamer development services to screening aptamers binds to the FLI1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | FLI1 |
| Alternative Names | EWSR2; SIC-1; BDPLT21 |
| Gene ID | 2313 |
| UniProt ID | Q01543 |
| Target Overview | This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |