Anti-GPA33 Aptamer SELEX Service(Cat#: CTApt-2338)

This is an aptamer development services to screening aptamers binds to the GPA33 with an affinity of 1nM~1μM.

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Certificate of Analysis Lookup

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Summary

Specifications
Target Category Protein
Target GPA33
Alternative Names Glycoprotein A33; Glycoprotein A33 (Transmembrane) ; Cell Surface A33 Antigen; A33; Transmembrane Glycoprotein A33; GPA33
Gene ID 10223
UniProt ID Q99795
Target Overview The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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