Anti-HGF Aptamer(Cat#: CTApt-M-1662)
This product is an aptamer which binds to the HGF with an affinity of <20 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
HGF |
| Alternative Names |
Hepatocyte Growth Factor; HPTA ; SF; F-TCF ; HGFB ; Hepatocyte Growth Factor (Hepapoietin A; Scatter Factor) ; Fibroblast-Derived Tumor Cytotoxic Factor ; Lung Fibroblast-Derived Mitogen; Hepatopoietin-A ; Scatter Factor ; DFNB39 ; Deafness, Autosomal Recessive 39 ; Hepatopoietin A ; EC 3.4.21.7; EC 3.4.21 |
| Gene ID |
3082 |
| UniProt ID |
P14210 |
| Target Overview |
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. |
| Chemical Modification |
DNA |
| Length |
100-150 nt |
| Affinity (Kd) |
<20 nM |
| Binding Conditions/Buffer |
Binding Buffer (PBS containing 1 mM MgCl2) |
| GC Content |
55.88% |
| Molecular Weight |
31366.29 g/mole |
| Extinction Coefficient |
928300 L/(mole·cm) |
| nmoles/OD260 |
1.08 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
