This product is an aptamer which binds to the H4 N-terminal tail with an affinity of <20 nM.
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| Target Category | Protein |
| Target | H4 N-terminal tail |
| Chemical Modification | DNA |
| Length | 40-60 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | Low-salt conditions: 100 mM NaCl, 5 mM MgCl2, and 10 mM HEPES (pH 7.5). High-salt conditions: 500 mM NaCl, 10 mM MgCl2, and 10 mM HEPES (pH 7.5). |
| GC Content | 0.6 |
| Molecular Weight | 15592.13 g/mole |
| Extinction Coefficient | 473300 L/(mole·cm) |
| nmoles/OD260 | 2.11 |
It is the gold standard in our labExcellentIt consistently performs well, and the data we've generated using it has been crucial for our publications. Highly recommended for serious researchers.
I'm very impressed with this aptamerExcellentIt's highly specific and sensitive, making it a go-to choice for studying histone modifications. I haven't encountered any major issues so far.
A useful tool for my lab workExcellentI bought this aptamer for my project. It has improved the quality of my Western blots and ChIP assays.