Anti-HLA-G Aptamer SELEX Service(Cat#: CTApt-770)

This is an aptamer development services to screening aptamers binds to the HLA-G with an affinity of 1nM~1μM.

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3’ Modification
 
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Lot Number

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Summary

Specifications
Target Category Protein
Target HLA-G
Alternative Names MHC-G
Gene ID 3135
UniProt ID P17693
Target Overview HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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