Anti-Human α1-antitrypsin Aptamer(Cat#: CTMM-0124-TT10)
This product is an aptamer which binds to the Human α1-antitrypsin with an affinity of high affinity.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
Alpha-1-antitrypsin |
| Alternative Names |
SERPINA1; Serpin Family A Member 1; Alpha-1-Antitrypsin; AAT; Alpha1AT; A1AT; A1A; PI1; PI; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1; Alpha-1 Proteinase Inhibitor; Alpha-1 Protease Inhibitor; Alpha-1-Antiproteinase; Alpha-1 Antitrypsin; Anti-Elastase; Serpin A1; Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1; Serpin Peptidase Inhibitor Clade A (Alpha-1antiproteinase, Antitrypsin) Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade A, Member 1; Protease Inhibitor 1 (Anti-Elastase), Alpha-1-Antitrypsin; Serpin Peptidase Inhibitor Clade A Member 1; Epididymis Secretory Sperm Binding Protein; Protease Inhibitor 1; PRO2275; NNIF |
| Gene ID |
5265 |
| UniProt ID |
P01009 |
| Target Overview |
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
<50 nt |
| Binding Conditions/Buffer |
PBS |
| GC Content |
64.86% |
| Molecular Weight |
11394.41 g/mole |
| nmoles/OD260 |
2.82 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
