Anti-Human AGER Aptamer(Cat#: CTMM-0124-RJ1)

This product is an aptamer which binds to Human AGER with an affinity of 1-50 nM.

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Summary

Specifications
Target Category Protein
Target AGER
Alternative Names Advanced Glycosylation End-Product Specific Receptor; RAGE; SCARJ1; SRAGE; Advanced Glycosylation End Product-Specific Receptor; Receptor For Advanced Glycation End-Products; Receptor For Advanced Glycosylation End Products; AGER
Gene ID 177
UniProt ID Q15109
Target Overview The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene.
Type DNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer 2 M NaCl, 1 mM ethylenediaminetetraacetic acid, 10 mM Tris-HCl, pH 7.5
GC Content 50.00%
Molecular Weight 24630 g/mole
nmoles/OD260 1.183
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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