This product is an aptamer which binds to human CCN2 with an affinity of 1-50 nM.
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| Target Category | Protein |
| Target | CCN2 |
| Alternative Names | Cellular Communication Network Factor 2; IGFBP8; Connective Tissue Growth Factor; CTGF; Hypertrophic Chondrocyte-Specific Protein 24; Insulin-Like Growth Factor-Binding Protein 8; IGF-Binding Protein 8; CCN Family Member 2; HCS24; IBP-8; IGFBP-8; NOV2 |
| Gene ID | 1490 |
| UniProt ID | P29279 |
| Target Overview | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. |
| Type | DNA |
| Species Reactivity | Human |
| Length | <50 nt |
| Affinity (Kd) | 1-50 nM |
| GC Content | 56.10% |
| Molecular Weight | 12119.9 g/mole |
| nmoles/OD260 | 2.389 |