Anti-Human CCR7 Aptamer(Cat#: CTMM-0124-LH9)
This product is an aptamer which binds to Human CCR7 domain with an affinity of 1-50 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
CCR7 |
| Alternative Names |
C-C Motif Chemokine Receptor 7; CDw197; BLR2; CMKBR7; CD197; EBI1; Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1; Chemokine (C-C Motif) Receptor 7; C-C Chemokine Receptor Type 7; MIP-3 Beta Receptor; CC-CKR-7; CCR-7; Lymphocyte-Specific G Protein-Coupled Peptide Receptor; EBV-Induced G Protein-Coupled Receptor 1; EBV-Induced G-Protein Coupled Receptor 1; Epstein-Barr Virus Induced Gene 1; Bukitt'S Lymphoma Receptor; CC Chemokine Receptor 7; CD197 Antigen; C-C CKR-7; EVI1 |
| Gene ID |
1236 |
| UniProt ID |
P32248 |
| Target Overview |
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
<50 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
DPBS, 1 mM CaCl2, 2.7 mM KCl, 1.47 mM KH2PO4, 1 mM MgCl2, 136.9 mM NaCl, 2.13 mM Na2HPO4, pH=7.0 ~ 7.4 |
| GC Content |
50.00% |
| Molecular Weight |
9153 g/mole |
| nmoles/OD260 |
3.612 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
