Anti-Human CD123 Aptamer(Cat#: CTMM-0124-RJ35)
This product is an aptamer which binds to Human CD123 with an affinity of 1-50 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
IL3RA |
| Alternative Names |
Interleukin 3 Receptor Subunit Alpha; CD123; Interleukin 3 Receptor, Alpha (Low Affinity); Interleukin-3 Receptor Subunit Alpha; IL-3 Receptor Subunit Alpha; IL-3R Subunit Alpha; CD123 Antigen; IL-3R-Alpha; IL3R; HIL-3Ra; IL3RAY; IL-3RA; IL3RX; IL3RY; IL3RA |
| Gene ID |
3563 |
| UniProt ID |
P26951 |
| Target Overview |
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. |
| Type |
DNA |
| Species Reactivity |
Human; Mouse |
| Length |
50-100 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
0.2 M sodium dihydrogen phosphate and 0.2 M sodium hydrogen phosphate |
| GC Content |
55.88% |
| Molecular Weight |
20357.2 g/mole |
| nmoles/OD260 |
1.511 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
