Anti-Human CD14 Aptamer(Cat#: CTMM-0724-TT3)

This product is an aptamer which binds to the human CD14 with an affinity of 50-100 nM.

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Summary

Specifications
Target Category Protein
Target CD14
Alternative Names Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein
Gene ID 929
UniProt ID P08571
Target Overview The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein.
Type DNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 1-50 nM
GC Content 46.15%
Molecular Weight 16149.58
Extinction Coefficient 526500
nmoles/OD260 1.89934
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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