This product is an aptamer which binds to Human CD40LG with an affinity of 1-50 nM.
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| Target Category | Protein |
| Target | CD40LG |
| Alternative Names | CD40 Ligand; CD40-L; CD40L; TRAP; TNF-Related Activation Protein; HCD40L; TNFSF5; CD154; HIGM1; T-BAM; Tumor Necrosis Factor (Ligand) Superfamily Member 5; T-B Cell-Activating Molecule; CD40 Antigen Ligand; T-Cell Antigen Gp39; Gp39; IMD3; Tumor Necrosis Factor (Ligand) Superfamily, Member 5 (Hyper-IgM Syndrome); Tumor Necrosis Factor Ligand Superfamily Member 5; Hyper-IgM Syndrome; CD154 Antigen; GP39; IGM; CD40LG |
| Gene ID | 959 |
| UniProt ID | P29965 |
| Target Overview | The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. |
| Type | DNA |
| Species Reactivity | Human |
| Length | <50 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | DPBS, 4.5 g/L glucose, 5 mM MgCl2, 100 mg/L, tRNA, and 1 g/L BSA |
| GC Content | 54.55% |
| Molecular Weight | 13168.6 g/mole |
| nmoles/OD260 | 2.196 |