This product is an aptamer which binds to the Human CXCL5 with an affinity of 50-200 pM.
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| Target Category | Protein |
| Target | CXCL5 |
| Alternative Names | C-X-C Motif Chemokine Ligand 5; ENA-78; SCYB5; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 5 (Epithelial-Derived Neutrophil-Activating Peptide 78); Epithelial-Derived Neutrophil-Activating Protein 78; Neutrophil-Activating Peptide ENA-78; Chemokine (C-X-C Motif) Ligand 5; C-X-C Motif Chemokine 5; Neutrophil-Activating Protein 78; Small-Inducible Cytokine B5; ENA-78(1-78); ENA78 |
| Gene ID | 6374 |
| UniProt ID | P42830 |
| Target Overview | This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. |
| Type | DNA |
| Species Reactivity | Human |
| Length | 50-100 nt |
| Affinity (Kd) | 50-200 pM |
| Binding Conditions/Buffer | DPBS with herring sperm DNA, BSA, tween-20 and 1.25mM MgCl₂ |
| GC Content | 53.95% |
| Molecular Weight | 23746.45 g/mole |
| nmoles/OD260 | 1.35 |