Anti-Human EN2 Aptamer(Cat#: CTMM-0124-LH24)

This product is an aptamer which binds to Human EN2 domain with an affinity of 1-50 nM.

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Summary

Specifications
Target Category Protein
Target EN2
Alternative Names Engrailed Homeobox 2; Homeobox Protein Engrailed-2; Homeobox Protein En-2; Hu-En-2; Engrailed Homolog; Engrailed-2
Gene ID 2020
UniProt ID P19622
Target Overview omeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
Type DNA
Species Reactivity Human
Length <50 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer Tris with MgCl2 and tween-20
GC Content 55.77%
Molecular Weight 16455 g/mole
nmoles/OD260 1.702
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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