Name: Anti-Human EPHB2 Aptamer
SKU: CTMM-0124-TT21
Rating: 5 (1 reviews)

Specifications

Target Category	Protein
Target	EPHB2
Alternative Names	EPH Receptor B2 EPHT3 HEK5 DRT ERK Developmentally-Regulated Eph-Related Tyrosine Kinase Tyrosine-Protein Kinase Receptor EPH-3 Renal Carcinoma Antigen NY-REN-47 Tyrosine-Protein Kinase TYRO5 Ephrin Type-B Receptor 2 EPH-Like Kinase 5 Tyro5 TYRO5 Hek5 EK5 Protein-Tyrosine Kinase HEK5 Elk-Related Tyrosine Kinase ELK-Related Tyrosine Kinase Eph Tyrosine Kinase 3 EPH Tyrosine Kinase 3 BDPLT22 3 EphB2 EPTH3 CAPB PCBC
Gene ID	2048
UniProt ID	P29323
Target Overview	This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
Chemical Modification	2'-fluoro pyrimidines
Type	RNA
Species Reactivity	Human
Length	<50 nt
Affinity (Kd)	200-1000 nM
Binding Conditions/Buffer	PBS, 1 mM MgCl₂, and 0.15% Tween-20, pH 7.4
GC Content	42.11%
Molecular Weight	11614.50 g/mole
nmoles/OD260	2.67

Anti-Human EPHB2 Aptamer(Cat#: CTMM-0124-TT21)

Certificate of Analysis Lookup

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