Anti-Human EPHB3 Aptamer(Cat#: CTMM-0124-TT22)
This product is an aptamer which binds to the Human EPHB3 with an affinity of 200-1000 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
EPHB3 |
| Alternative Names |
EPH Receptor B3; HEK2; TYRO6; ETK2; Tyrosine-Protein Kinase TYRO6; EPH-Like Tyrosine Kinase 2; Ephrin Type-B Receptor 3; Embryonic Kinase 2; EK2; Human Embryo Kinase 2; EPH-Like Kinase 2; Tyro6; EphB3; Hek2 |
| Gene ID |
2049 |
| UniProt ID |
P54753 |
| Target Overview |
This gene encodes a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. |
| Chemical Modification |
2'-fluoro pyrimidines |
| Type |
RNA |
| Species Reactivity |
Human |
| Length |
<50 nt |
| Affinity (Kd) |
200-1000 nM |
| Binding Conditions/Buffer |
PBS, 1 mM MgCl₂, and 0.15% Tween-20, pH 7.4 |
| GC Content |
42.11% |
| Molecular Weight |
11614.50 g/mole |
| nmoles/OD260 |
2.67 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
