Anti-Human ERK2 Aptamer(Cat#: CTMM-0124-TT28)

This product is an aptamer which binds to the Human ERK2 with an affinity of 1-50 nM.

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Specifications
Target Category Protein
Target MAPK1
Alternative Names Mitogen-Activated Protein Kinase 1; ERK2; Extracellular Signal-Regulated Kinase 2; MAPK2; PRKM1; PRKM2; ERK; Mitogen-Activated Protein Kinase 2; MAP Kinase 1; MAP Kinase 2; P42-MAPK; P41mapk; MAPK 2; ERK-2; ERT1; Protein Tyrosine Kinase ERK2; MAP Kinase Isoform P42; P42MAPK; P41MAPK; MAPK 1; NS13; P38; P40; P41
Gene ID 5594
UniProt ID P28482
Target Overview This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Type RNA
Species Reactivity Human
Length 100-200 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer PBS with 3 mM MgCl₂ and 0.8 μg/μL Heparin
GC Content 52.48%
Molecular Weight 31175.84 g/mole
nmoles/OD260 1.02

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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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