Anti-Human FGF5 Aptamer(Cat#: CTMM-0124-TT42)

This product is an aptamer which binds to the Human FGF5 with an affinity of 50-200 pM.

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Summary

Specifications
Target Category Protein
Target FGF5
Alternative Names Fibroblast Growth Factor 5; Heparin-Binding Growth Factor 5; Smag-82; HBGF-5; TCMGLY; FGF-5
Gene ID 2250
UniProt ID P12034
Target Overview The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Chemical Modification 2'-fluoro pyrimidines
Type RNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 50-200 pM
Binding Conditions/Buffer 20 mM Tris-HCl, 200 mM NaCl, 5 mM MgCl₂, 5 mM CaCl₂, 0.05% Tween 20, 10% glycerol, pH 7.4
GC Content 57.14%
Molecular Weight 16975.79 g/mole
nmoles/OD260 1.94
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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