This product is an aptamer which binds to human HBEGF with an affinity of 1-50 nM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | HBEGF |
| Alternative Names | Heparin Binding EGF Like Growth Factor; HEGFL; DTR; DTS; Diphtheria Toxin Receptor (Heparin-Binding Epidermal Growth Factor-Like Growth Factor); Diphtheria Toxin Receptor (Heparin-Binding EGF-Like Growth Factor); Proheparin-Binding EGF-Like Growth Factor; Heparin-Binding Epidermal Growth Factor; Heparin-Binding EGF-Like Growth Factor; DTSF |
| Gene ID | 1839 |
| UniProt ID | Q99075 |
| Target Overview | Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. |
| Chemical Modification | 2'-fluoro pyrimidines |
| Type | RNA |
| Species Reactivity | Human |
| Length | 100-200 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | 40 mmol/L HEPES, 200 mmol/L NaCl, 20 mmol/L MgCl2, and 100 mmol/L KCl, pH 7.2 |
| GC Content | 55.08% |
| Molecular Weight | 35580.7 g/mole |
| nmoles/OD260 | 0.769 |