Anti-Human HMGA2 Aptamer(Cat#: CTWZ-0124-WZ33)

This product is an aptamer which binds to human HMGA2 with a high affinity.

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Summary

Specifications
Target Category Protein
Target HMGA2
Alternative Names High Mobility Group AT-Hook 2; HMGIC; BABL; LIPO; High Mobility Group Protein HMGI-C; High-Mobility Group (Nonhistone Chromosomal) Protein Isoform I-C; High Mobility Group AT-Hook Protein; HMGA2/KRT121P Fusion; HMGI-C; STQTL9; SRS5
Gene ID 8091
UniProt ID P52926
Target Overview This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Chemical Modification 2'-fluoro pyrimidines
Type DNA
Species Reactivity Human
Length <50 nt
GC Content 23.08%
Molecular Weight 7376.9 g/mole
nmoles/OD260 3.449
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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