This product is an aptamer which binds to Human ICAM1 domain with an affinity of 1-50 nM.
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| Target Category | Protein |
| Target | ICAM1 |
| Alternative Names | Intercellular Adhesion Molecule 1; CD54; BB2; Major Group Rhinovirus Receptor; ICAM-1; Intercellular Adhesion Molecule 1 (CD54), Human Rhinovirus Receptor; Epididymis Secretory Sperm Binding Protein; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; CD54 Antigen; P3.58 |
| Gene ID | 3383 |
| UniProt ID | P05362 |
| Target Overview | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. |
| Type | DNA |
| Species Reactivity | Human |
| Length | 50-100 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | CS-BB, 1 mg/mL BSA and 0.1 mg/mL yeast tRNA, 4.5 g/L glucose and 5 mM MgCl2 in DPBS, pH=7.4 |
| GC Content | 53.01% |
| Molecular Weight | 24514.9 g/mole |
| nmoles/OD260 | 1.301 |