Anti-Human IFNA1 Aptamer(Cat#: CTMM-0124-RJ20)

This product is an aptamer which binds to Human IFNA1 with an affinity of 1-50 nM.

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Summary

Specifications
Target Category Protein
Target IFNA1
Alternative Names Interferon Alpha 1; IFN-ALPHA; IFNA13; IFNA@; IFL; IFN; Interferon Alpha-1/13; Interferon Alpha 1b; Interferon Alpha-D; IFN-Alpha-1/13; IFN-AlphaD; LeIF D; Interferon-Alpha1; IFN-Alpha 1b; IFN-ALPHAD; IFNA1
Gene ID 3439
UniProt ID P01562
Target Overview This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
Type DNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer 100 mM carbonate-bicarbonate buffer, pH 9.6
GC Content 51.22%
Molecular Weight 24529.9 g/mole
nmoles/OD260 1.243
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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