This product is an aptamer that binds to the Human Lag3 with an affinity of <50 nM.
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| Target Category | Protein |
| Target | LAG3 |
| Alternative Names | Lymphocyte Activating 3; CD223; Lymphocyte Activation Gene 3 Protein; Lymphocyte-Activation Gene 3; CD223 Antigen; LAG-3; FDC |
| Gene ID | 3902 |
| UniProt ID | P18627 |
| Target Overview | Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. |
| Type | RNA |
| Species Reactivity | Human |
| Length | 50-200 nt |
| Affinity (Kd) | <50 nM |
| Binding Conditions/Buffer | 20mM HEPES, 150 mM NaCl, 2mM CaCl₂ and 0.01% BSA |
| GC Content | 51.39% |
| Molecular Weight | 21205.44 g/mole |
| nmoles/OD260 | 1.61 |