Anti-Human Lag3 Aptamer(Cat#: CTMM-0124-JS22)

This product is an aptamer that binds to the Human Lag3 with an affinity of <50 nM.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target LAG3
Alternative Names Lymphocyte Activating 3; CD223; Lymphocyte Activation Gene 3 Protein; Lymphocyte-Activation Gene 3; CD223 Antigen; LAG-3; FDC
Gene ID 3902
UniProt ID P18627
Target Overview Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
Type RNA
Species Reactivity Human
Length 50-200 nt
Affinity (Kd) <50 nM
Binding Conditions/Buffer 20mM HEPES, 150 mM NaCl, 2mM CaCl₂ and 0.01% BSA
GC Content 51.39%
Molecular Weight 21205.44 g/mole
nmoles/OD260 1.61
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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