Anti-Human MAX Aptamer(Cat#: CTMM-0124-JS6)
This product is an aptamer that binds to the Human MAX protein with an affinity of 50-200 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
MAX |
| Alternative Names |
MYC Associated Factor X; BHLHd4; Class D Basic Helix-Loop-Helix Protein 4; Protein Max; BHLHD4; Myc-Associated Factor X; MAX Protein; BHLHd5; BHLHd6; BHLHd7; BHLHd8; BHLHD5; BHLHD6; BHLHD7; BHLHD8 |
| Gene ID |
4149 |
| UniProt ID |
P61244 |
| Target Overview |
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
50-200 nt |
| Affinity (Kd) |
50-200 nM |
| Binding Conditions/Buffer |
13.5 mM NaCl, 100 mM KCl, 0.22 mM Na₂HPO₄, 5 mM MgSO₄, 120 nM CaCl₂, 5 mM MgCl₂, 0.05% NP40, 20 mM HEPES, pH7.25 |
| GC Content |
55.17% |
| Molecular Weight |
26579.26 g/mole |
| nmoles/OD260 |
1.24 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
