Anti-Human/Mouse CXCL10 Aptamer(Cat#: CTMM-0124-JS31)

This product is an aptamer that binds to the Human CXCL10 with an affinity of <50 nM.

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Specifications
Target Category Protein
Target CXCL10
Alternative Names CXCL10,C-X-C Motif Chemokine Ligand 10,IP-10 ,GIP-10 ,SCYB10,IFI10,Crg-2,Mob-1 ,INP10 ,C7 ,Small Inducible Cytokine Subfamily B (Cys-X-Cys); Member 10 ,10 KDa Interferon Gamma-Induced Protein ,Small-Inducible Cytokine B10 ,C-X-C Motif Chemokine 10 ,Protein 10 From Interferon (Gamma)-Induced Cell Line ,Interferon-Inducible Cytokine IP-10 ,Chemokine (C-X-C Motif) Ligand 10 ,Gamma IP10 ,Gamma-IP10
Gene ID 3627
UniProt ID P02778
Target Overview This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020]
Type RNA
Species Reactivity Human; Mouse
Length 50-200 nt
Affinity (Kd) <50 nM
Binding Conditions/Buffer 110 mM NaCl, 1 mM MgCl₂, 20 mM HEPES, pH 7.0, 1 mM CaCl₂, 5 mM KCl
GC Content 58.90%
Molecular Weight 21723.80 g/mole
nmoles/OD260 1.59

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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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