This product is an aptamer which binds to Human and Mouse PD-L1 with an affinity of 1-50 nM.
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| Target Category | Protein |
| Target | PD-L1 |
| Alternative Names | CD274 Molecule; B7H1; PDL1; Programmed Cell Death 1 Ligand 1; CD274 Antigen; B7 Homolog 1 |
| Gene ID | 29126 |
| UniProt ID | Q9NZQ7 |
| Target Overview | PD-L1 is a 40kDa transmembrane protein that is closely related to the suppression of the immune system in specific events, such as pregnancy, tissue allografting and autoimmune diseases. |
| Type | DNA |
| Species Reactivity | Human; Mouse |
| Length | <50 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | 150 mmol/l NaCl, 5 mmol/l KCl, 1 mmol/l MgCl₂, 1 mmol/l CaCl₂ and 40 mmol/l HEPES, pH 7.4 |
| GC Content | 53.33% |
| Molecular Weight | 13734.95 g/mole |
| nmoles/OD260 | 2.35 |