Anti-Human PDE1C Aptamer(Cat#: CTMM-0124-RJ47)

This product is an aptamer which binds to Human PDE1C with a high affinity.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target PDE1C
Alternative Names Phosphodiesterase 1C; Dual Specificity Calcium/Calmodulin-Dependent 3',5'-Cyclic Nucleotide; Phosphodiesterase 1C; Hcam3; Phosphodiesterase 1C, Calmodulin-Dependent 70kDa; EC 3.1.4.17; Cam-PDE 1C; Calcium/Calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1C; Human 3',5' Cyclic Nucleotide Phosphodiesterase (HSPDE1C1A); Phosphodiesterase 1C, Calmodulin-Dependent (70kD); 3',5'-Cyclic-AMP Phosphodiesterase; 3',5'-Cyclic-GMP Phosphodiesterase; EC 3.1.4; DFNA74; HCam-3; HCAM3; PDE1C
Gene ID 5137
UniProt ID Q14123
Target Overview This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
Type DNA
Species Reactivity Human
Length 100-200 nt
Binding Conditions/Buffer 25mM glucose, 0.1% BSA, 0.25 mM MgCl2 and PBS
GC Content 50.93%
Molecular Weight 32208.8 g/mole
nmoles/OD260 0.971
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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