Anti-Human PKM Aptamer(Cat#: CTMM-0124-RJ67)
This product is an aptamer which binds to Human PKM with a high affinity.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
PKM |
| Alternative Names |
Pyruvate Kinase M1/2; THBP1; OIP3; PK3; PKM2; Cytosolic Thyroid Hormone-Binding Protein; Thyroid Hormone-Binding Protein 1; Pyruvate Kinase Muscle Isozyme; Threonine-Protein Kinase PKM2; Tyrosine-Protein Kinase PKM2; Pyruvate Kinase, Muscle; Pyruvate Kinase PKM; Pyruvate Kinase 2/3; Tumor M2-PK; EC 2.7.1.40; CTHBP; P58; Thyroid Hormone-Binding Protein, Cytosolic; Epididymis Secretory Protein Li 30; Pyruvate Kinase Isozymes M1/M2; OPA-Interacting Protein 3; Opa-Interacting Protein 3; PK, Muscle Type; EC 2.7.11.1; EC 2.7.10.2; HEL-S-30; OIP-3; TCB; PK2; PKM |
| Gene ID |
5315 |
| UniProt ID |
P14618 |
| Target Overview |
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. |
| Type |
Peptide |
| Species Reactivity |
Human |
| Length |
<50 nt |
| Binding Conditions/Buffer |
2% galactose/1% raffinose minimal medium, Ura−, His−, Trp− |
| Molecular Weight |
2332.7 g/mole |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
