Anti-Human PPY Aptamer(Cat#: CTMM-0124-LH34)
This product is an aptamer which binds to Human PPY domain with an affinity of 1-50 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
PPY |
| Alternative Names |
Pancreatic Polypeptide; PNP; Pancreatic Polypeptide Y; Prepro-PP (Prepropancreatic Polypeptide); Pancreatic Polypeptide Prohormone; PH; Pancreatic Prohormone; Obinepitide; PP |
| Gene ID |
5539 |
| UniProt ID |
P01298 |
| Target Overview |
This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
<50 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
20 mM Hepes, 120 mM NaCl, 5 mM KCl, 2 mM MgCl2, pH=7.4 |
| GC Content |
59.46% |
| Molecular Weight |
10789 g/mole |
| nmoles/OD260 |
2.743 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
