Anti-Human Prothrombin Aptamer(Cat#: CTMM-0124-RJ61)
This product is an aptamer which binds to Human Prothrombin with an affinity of 1-50 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
Prothrombin |
| Target Overview |
Thrombin is a serine protease, an enzyme that, in humans, is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the clotting process. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. |
| Chemical Modification |
2'-fluoro pyrimidines |
| Type |
RNA |
| Species Reactivity |
Human |
| Length |
50-100 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
20 mM Hepes, 150 mM NaCl and 2 mM CaCl2, pH 7.4 |
| GC Content |
51.67% |
| Molecular Weight |
17752.4 g/mole |
| nmoles/OD260 |
1.527 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
