Anti-Human RENBP Aptamer(Cat#: CTMM-0124-RJ2)

This product is an aptamer which binds to Human RENBP with an affinity of 200-1000 pM.

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Summary

Specifications
Target Category Protein
Target RENBP
Alternative Names Renin Binding Protein; N-Acetyl-D-Glucosamine 2-Epimerase; N-Acylglucosamine 2-Epimerase; GlcNAc 2-Epimerase; RNBP; RBP; Renin-Binding Protein; EC 5.1.3.8; AGE; RnBP; RENBP
Gene ID 5973
UniProt ID P51606
Target Overview The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature.
Chemical Modification Phosphorothioate
Type DNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 200-1000 pM
Binding Conditions/Buffer 2 M NaCl, 1 mM ethylenediaminetetraacetic acid, 10 mM Tris-HCl, pH 7.5
GC Content 50.00%
Molecular Weight 24465.9 g/mole
nmoles/OD260 1.18
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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