Anti-Human STIP1 Aptamer(Cat#: CTWZ-0124-WZ50)

This product is an aptamer which binds to human STIP1 with a high affinity.

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Summary

Specifications
Target Category Protein
Target STIP1
Alternative Names Stress Induced Phosphoprotein 1; STI1; Stress-Induced-Phosphoprotein 1; HOP; Transformation-Sensitive Protein IEF SSP 3521; Renal Carcinoma Antigen NY-REN-11; Hsp70/Hsp90-Organizing Protein; Hsc70/Hsp90-Organizing Protein; Epididymis Secretory Sperm Binding Protein Li 94n; NY-REN-11 Antigen; IEF-SSP-3521; HEL-S-94n; STI1L; P60; Hop
Gene ID 10963
UniProt ID P31948
Target Overview STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).
Type DNA
Species Reactivity Human
Length 50-100 nt
Binding Conditions/Buffer PBS with CaCl2 and MgCl2, with Baker's yeast tRNA (0.1 mg/mL), BSA (1 mg/mL), 4.5 g/L glucose and 5 mM MgCl2.
GC Content 48.72%
Molecular Weight 23311.2 g/mole
nmoles/OD260 1.282
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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