Anti-Human VWF Aptamer(Cat#: CTMM-0124-LH61)

This product is an aptamer which binds to Human VWF with an affinity of 1-50 nM.

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Specifications
Target Category Protein
Target Von Willebrand Factor (VWF)
Alternative Names Von Willebrand Factor; F8VWF; Factor VIII Related Antigen; Coagulation Factor VIII VWF; VWD
Gene ID 7450
UniProt ID P04275
Target Overview This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.
Chemical Modification 2'-O-methyl oligonucleotides
Type RNA
Species Reactivity Human; Monkey
Length <50 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer PBS
GC Content 47.78%
Molecular Weight 9501.6 g/mole
nmoles/OD260 2.879
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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